Simone Brogi Selected Research

1- (5- (4- bromo- 2- chlorophenyl)furan- 2- yl)- N- ((piperidin- 4- yl)methyl)methanamine

4/2018

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.

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Simone Brogi Research Topics

Disease

9	Neoplasms (Cancer) 05/2022 - 01/2016
6	Neuroblastoma 01/2021 - 01/2017
6	Infections 11/2019 - 08/2012
4	Alzheimer Disease (Alzheimer's Disease) 10/2020 - 01/2015
4	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2020 - 01/2017
3	Pain (Aches) 01/2016 - 03/2012
2	Carcinoma (Carcinomatosis) 05/2022 - 10/2021
2	Idiopathic Pulmonary Fibrosis 01/2021 - 01/2020
2	Epilepsy (Aura) 01/2021 - 03/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 10/2020
2	COVID-19 11/2020 - 01/2020
2	Inflammation (Inflammations) 09/2020 - 01/2020
2	Rett Syndrome (Rett's Disorder) 01/2020 - 01/2018
2	Leishmaniasis 06/2019 - 01/2016
2	Hypersensitivity (Allergy) 10/2018 - 01/2016
2	Neuralgia (Stump Neuralgia) 10/2018 - 01/2017
2	Malaria 04/2018 - 08/2012
1	Starvation 05/2022
1	Squamous Cell Carcinoma of Head and Neck 05/2022
1	Parasitic Diseases (Parasitic Disease) 04/2022
1	Pathologic Processes 01/2022
1	Airway Remodeling 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Ischemia 10/2021
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2021
1	Temporal Lobe Epilepsy 01/2021
1	Hyperhomocysteinemia 01/2021
1	Atherosclerosis 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Seizures (Absence Seizure) 01/2021
1	Pneumonia (Pneumonitis) 11/2020
1	Schistosomiasis (Bilharziasis) 10/2020
1	Rare Diseases (Rare Disease) 01/2020
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2020
1	Extensively Drug-Resistant Tuberculosis 11/2019
1	Central Nervous System Diseases (CNS Diseases) 03/2019
1	Photophobia (Light Sensitivity) 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 12/2017
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 02/2017

Drug/Important Bio-Agent (IBA)

9	Pharmaceutical PreparationsIBA 10/2020 - 08/2012
6	Biological ProductsIBA 01/2022 - 01/2017
5	Proteins (Proteins, Gene)FDA Link 05/2022 - 01/2016
5	EnzymesIBA 10/2021 - 01/2016
3	Histone Deacetylases (Histone Deacetylase)IBA 10/2021 - 01/2016
3	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2021 - 10/2020
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2018 - 01/2016
2	TubulinIBA 05/2022 - 01/2018
2	Peptides (Polypeptides)IBA 01/2022 - 01/2015
2	Amyloid (Amyloid Fibrils)IBA 09/2020 - 01/2017
2	LigandsIBA 01/2020 - 01/2017
2	ArginaseIBA 06/2019 - 01/2016
2	CarbamatesIBA 10/2018 - 09/2018
2	Tacrine (Cognex)FDA Link 01/2017 - 01/2015
1	NitrilesIBA 04/2022
1	Cysteine Proteases (Cysteine Protease)IBA 04/2022
1	polyarginineIBA 01/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022
1	Prednisone (Sone)FDA LinkGeneric 01/2022
1	AmidesIBA 01/2022
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	NF-kappa B (NF-kB)IBA 01/2021
1	EndocannabinoidsIBA 01/2021
1	GasotransmittersIBA 01/2021
1	Histone Deacetylase InhibitorsIBA 11/2020
1	CytokinesIBA 11/2020
1	Antiviral Agents (Antivirals)IBA 11/2020
1	Praziquantel (Biltricide)FDA Link 10/2020
1	AcetylcholinesteraseIBA 10/2020
1	Amyloid beta-PeptidesIBA 10/2020
1	MicroRNAs (MicroRNA)IBA 10/2020
1	Neuroprotective AgentsIBA 09/2020
1	Olive OilIBA 09/2020
1	Protein Isoforms (Isoforms)IBA 04/2020
1	GoldIBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2020
1	HDL CholesterolIBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Histone Deacetylase 6IBA 01/2020
1	imetelstatIBA 01/2020
1	peptide deformylaseIBA 11/2019
1	QuercetinIBA 06/2019
1	Ionotropic Glutamate ReceptorsIBA 03/2019
1	HIV IntegraseIBA 01/2019
1	Ion Channels (Ion Channel)IBA 01/2019
1	artemisinin (artemisinine)IBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 10/2018
1	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 10/2018
1	1- (5- (4- bromo- 2- chlorophenyl)furan- 2- yl)- N- ((piperidin- 4- yl)methyl)methanamineIBA 04/2018
1	methylamine (methylammonium)IBA 04/2018
1	furanIBA 04/2018
1	Antimalarials (Antimalarial Agents)IBA 04/2018
1	LuciferasesIBA 12/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2017
1	AntioxidantsIBA 09/2017
1	Fluorescent Dyes (Fluorescent Probes)IBA 02/2017

Therapy/Procedure

8	Therapeutics 05/2022 - 04/2018